Hydrochloric Acid → HCID 88176490, compound

HRID 1952817Notes

Reaction equation

HRID 1952817 reaction equation
[ClH:1].[CH2:2]([N:6]([CH2:42][CH2:43][CH2:44][CH3:45])[CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N:21]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH:22]=[O:23])=[O:12])[CH2:3][CH2:4][CH3:5]>C(OCC)(=O)C>[ClH:1].[CH2:42]([N:6]([CH2:2][CH2:3][CH2:4][CH3:5])[CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N:21]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])[CH:22]=[O:23])=[O:12])[CH2:43][CH2:44][CH3:45]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53979910HCID 53979910, compound

Product 1

HCID 88176490HCID 88176490, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (1.36 ml) was added to a solution of [2-[[N-[3-(dibutylamino)propyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide (2.60 g) in ethyl acetate (26 ml) while being cooled with ice. After being stirred for 30 minutes, the reaction mixture was concentrated, thereby yielding 2.75 g of the aimed compound as white solid.

Workup

  1. temperaturewhile being cooled with ice
  2. concentrationthe reaction mixture was concentrated

Sources & evidence

ORD record
ord-0011b2efe78c4817b34dda2a8a08983c
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

Loading…