Diethyl Ether → Hydrochloric Acid

HRID 195297Notes

Reaction equation

HRID 195297 reaction equation
[CH3:35][CH2:36][O:37][CH2:38][CH3:39].[CH:31]([OH:32])([CH3:33])[CH3:34].[Cl:15][c:16]1[n:17][cH:18][n:19][c:20]2[cH:21][c:22]([O:26][CH2:27][CH2:28][CH2:29][Cl:30])[cH:23][cH:24][c:25]12.[NH2:1][c:2]1[cH:3][n:4][n:5]([CH2:7][C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[cH:6]1>>[ClH:15].[NH:1]([c:2]1[cH:3][n:4][n:5]([CH2:7][C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[cH:6]1)[c:16]1[n:17][cH:18][n:19][c:20]2[cH:21][c:22]([O:26][CH2:27][CH2:28][CH2:29][Cl:30])[cH:23][cH:24][c:25]12

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 3776IsopropanolHCID 162215144-Chloro-7-(3-chloropropoxy)quinazolineHCID 61285781tert-butyl 2-(4-amino-1H-pyrazol-1-yl)acetate

Product 2

HCID 313Hydrochloric AcidHCID 86609385tert-butyl (4-{[7-(3-chloropropoxy)quinazolin-4-yl]amino}-1H-pyrazol-1-yl)acetate

Sources & evidence

ORD record
ord-162fe9eed1694b7bae2a8dc6a04bed08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…