Methanol → 4-(4-Fluorophenyl)-3-hydroxymethylpiperidine-6-one
Reaction equation
[C:10]([CH2:11][CH2:14][CH:15]1[CH2:16][NH:17][C:18](=[O:28])[CH2:19][CH:20]1[c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1)([OH:12])=[O:13].[CH3:1][CH:2]([CH2:3][AlH:4][CH2:5][CH:6]([CH3:7])[CH3:8])[CH3:9].[CH3:29][OH:30].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[CH2:14]([CH:15]1[CH2:16][NH:17][C:18](=[O:28])[CH2:19][CH:20]1[c:21]1[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]1)[OH:30]Participants
6
Sources & evidence
- ORD record
- ord-0991a2eacaf54d2b8113a192ab0a8165
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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