HCID 53720842, compound → HCID 23297275, compound

HRID 1953362Notes

Reaction equation

HRID 1953362 reaction equation
C([O:8][C:9]([CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([C:21](=[O:31])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:17]=2)[CH2:12]1)=[O:10])C1C=CC=CC=1.[H][H]>[Pd].C1COCC1>[C:21]([C:16]1[CH:17]=[C:18]2[C:13](=[CH:14][CH:15]=1)[CH2:12][CH:11]([C:9]([OH:10])=[O:8])[CH2:20][CH2:19]2)(=[O:31])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]

Participants

5

Reactant 2

HCID 53720842HCID 53720842, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 23297275HCID 23297275, compoundYield 111.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

50 mL of a THF solution containing 3.79 g (8.69 mmol) of 6-decanoyl-1,2,3,4-tetrahydro-2-naphthalenecarboxylic acid benzyl ester and 0.43 g of 5% palladium/carbon was placed in a hydrogen atmosphere, using a baloon, and was stirred at room temperature for 24 hours. The reaction mixture was filtered and by concentrating the filtrate, there was obtained 3.19 g of 6-decanoyl-1,2,3,4-tetrahydro-2-naphthalenecarboxylic acid. The yield was 100%.

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationby concentrating the filtrate

Sources & evidence

ORD record
ord-6b2f66643ed04e0382b52a2ca7c7441a
Source dataset
uspto-grants-2000_09
Patent number
US06117359

Reaction notes

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