Water → HCID 23298017, compound

HRID 1953765Notes

Reaction equation

HRID 1953765 reaction equation
[N-:1]=[N+:2]=[N-:3].[Na+].[Br:5][C:6]1[CH:15]=[C:14]2[C:9]([N:10]=[C:11]([O:18][CH3:19])[C:12]([O:16][CH3:17])=[N:13]2)=[C:8]([CH2:20]Br)[CH:7]=1.O>CN(C)C=O>[N:1]([CH2:20][C:8]1[CH:7]=[C:6]([Br:5])[CH:15]=[C:14]2[C:9]=1[N:10]=[C:11]([O:18][CH3:19])[C:12]([O:16][CH3:17])=[N:13]2)=[N+:2]=[N-:3]

Participants

5

Reactant 3

HCID 962WaterHCID 33557Sodium AzideHCID 23298010HCID 23298010, compound

Product 1

HCID 23298017HCID 23298017, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

743 mg (2 eq.) of sodium azide are added at 20° to 2.07 g (5.72 mmol) of 7-bromo-5-bromomethyl-2,3-dimethoxyquinoxaline in 25 ml of dimethylformamide. After 3 hours, the mixture is poured into water, extracted with diethyl ether, and the extract is washed with water and brine and dried using magnesium sulfate. The solvent is evaporated.

Workup

  1. extractionextracted with diethyl ether
  2. washthe extract is washed with water and brine
  3. customdried
  4. customThe solvent is evaporated

Sources & evidence

ORD record
ord-834f314fd6d74c938c64cdfe70b7cf0b
Source dataset
uspto-grants-2000_09
Patent number
US06117873

Reaction notes

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