p-Toluenesulfonic acid monohydrate → 2-isopropylidene-1-indanone

HRID 1953947Notes

Reaction equation

HRID 1953947 reaction equation
[OH2:1].[C:2]1([CH3:12])[CH:7]=[CH:6][C:5](S(O)(=O)=O)=[CH:4][CH:3]=1>C1C=CC=CC=1>[C:2](=[C:3]1[CH2:4][C:7]2[C:2](=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:12]1=[O:1])([CH3:12])[CH3:7]

Participants

3

Reactant 1

HCID 521998p-Toluenesulfonic acid monohydrate

Product 1

HCID 15133342-isopropylidene-1-indanone

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

The reaction mixture was dissolved in 300 ml of benzene and 4.2 g of p-toluenesulfonic acid monohydrate was added to the solution and refluxed for 2 hours for component distillation. The product was used in the subsequent reaction without purification.

Workup

  1. temperaturerefluxed for 2 hours for component distillation
  2. customThe product was used in the subsequent reaction without purification

Sources & evidence

ORD record
ord-ec9a2c624181455a96b4fab23f811200
Source dataset
uspto-grants-2000_09
Patent number
US06121182

Reaction notes

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