Oxalyl chloride → HCID 23293624, compound

HRID 1954869Notes

Reaction equation

HRID 1954869 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:11]\[C:12]([OH:14])=O.C(Cl)(=O)C([Cl:18])=O>CN(C)C=O.ClCCl>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:11]\[C:12]([Cl:18])=[O:14]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 23293654HCID 23293654, compound

Product 1

HCID 23293624HCID 23293624, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneCatalystHCID 6228DimethylformamideSolvent

Procedure

A suspension of (E)-2-(4-chloro-1-indanylidene) acetic acid (5.5 g, 0.03 mol) in a mixture of dimethylformamide: dichloromethane (5 drops: 50 mL) was treated with oxalyl chloride (6.6 g, 0.05 mol) and allowed to stir at room temperature for 18 h. The resulting solution was concentrated in vacuo and the residue used without further purification.

Workup

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customthe residue used without further purification

Sources & evidence

ORD record
ord-fd332b0ce5d342a8b09caef0a1449bc0
Source dataset
uspto-grants-2000_09
Patent number
US06124284

Reaction notes

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