2-tert-Butylcyclohexanol → HCID 19070338, compound

HRID 1955503Notes

Reaction equation

HRID 1955503 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N+]([O-])=O)=[CH:5][C:4]=1[C:12]#[N:13])#[N:2].[C:14]([CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[OH:24])([CH3:17])([CH3:16])[CH3:15]>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([O:24][CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23][CH:18]2[C:14]([CH3:17])([CH3:16])[CH3:15])=[CH:5][C:4]=1[C:12]#[N:13])#[N:2]

Participants

3

Reactant 2

HCID 260682-tert-ButylcyclohexanolHCID 974431,2-Benzenedicarbonitrile, 4-nitro-

Product 1

HCID 19070338HCID 19070338, compoundYield 50%

Procedure

As in Synthesis Example 1 but using 1.73 grams of 1,2-dicyano-4-nitrobenzene and 4.7 grams of 2-t-butylcyclohexanol, there was obtained 1.41 grams of 1,2-dicyano-4-(2-t-butylcyclohexyloxy)benzene (yield of 50%). Next, as in Synthesis Example 1 but using 1.41 grams of this compound and 0.42 gram of BBr3, there was obtained 0.77 gram of the end product (yield 50%, mp 162°-165° C.).

Workup

  1. customAs in Synthesis Example 1

Sources & evidence

ORD record
ord-8de19d7aee81442b981c0dad23c212ed
Source dataset
uspto-grants-1998_07
Patent number
US05776656

Reaction notes

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