3-Methyl-1H-indol-1-amine → HCID 19072374, compound

HRID 1955668Notes

Reaction equation

HRID 1955668 reaction equation
[CH3:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]([NH2:11])[CH:3]=1.Cl.[Cl:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][C:19]=1Cl>C(O)(C)C>[ClH:13].[Cl:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][C:19]=1[NH:11][N:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:2]([CH3:1])=[CH:3]1

Participants

4

Reactant 2

HCID 124272923-Methyl-1H-indol-1-amineHCID 190723643,4-Dichloropyridine--hydrogen chloride (1/1)

Product 1

HCID 19072374HCID 19072374, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The title compound was prepared from 3-methyl-1H-indol-1-amine and 3,4-dichloropyridine hydrochloride in isopropanol at 80° C. for 5 hours in substantially the same manner as in Example 17. Recrystallized from ethanol, m.p. 278°-280° C. (dec.).

Workup

  1. customRecrystallized from ethanol, m.p. 278°-280° C. (dec.)

Sources & evidence

ORD record
ord-f88951566b2f4c96909563de7d49e711
Source dataset
uspto-grants-1998_07
Patent number
US05776955

Reaction notes

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