Hydrogen Bromide → HCID 14459513, compound

HRID 1957397Notes

Reaction equation

HRID 1957397 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]([S:26]([C:29]2[CH:34]=[CH:33][C:32]([CH2:35][CH2:36][C:37]([O:39]CC3C=CC=CC=3)=[O:38])=[CH:31][CH:30]=2)(=[O:28])=[O:27])[C:10]([C:12]2[C:13]3[C:18]([N:19]=[C:20]4[C:25]=2[CH:24]=[CH:23][CH:22]=[CH:21]4)=[CH:17][CH:16]=[CH:15][CH:14]=3)=[O:11])=[CH:5][CH:4]=1.C(OC(C)C)(C)C.[BrH:54]>>[BrH:54].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]([S:26]([C:29]2[CH:30]=[CH:31][C:32]([CH2:35][CH2:36][C:37]([OH:39])=[O:38])=[CH:33][CH:34]=2)(=[O:28])=[O:27])[C:10]([C:12]2[C:25]3[C:20]([N:19]=[C:18]4[C:13]=2[CH:14]=[CH:15][CH:16]=[CH:17]4)=[CH:21][CH:22]=[CH:23][CH:24]=3)=[O:11])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 7914Diisopropyl EtherHCID 14459511HCID 14459511, compound

Product 1

HCID 14459513HCID 14459513, compound

Procedure

6.3 g of (3) in 30 ml of 33% HBr/glacial acetic acid are ##STR16## heated at 60° C. for 2 hours and, after cooling, 60 ml of diisopropyl ether are added, and the precipitate is filtered off with suction and dried in vacuo:

Workup

  1. temperatureafter cooling
  2. filtrationthe precipitate is filtered off with suction
  3. customdried in vacuo

Sources & evidence

ORD record
ord-18e3ba419f3149d6ae05dc1ff3922525
Source dataset
uspto-grants-1998_07
Patent number
US05783696

Reaction notes

Loading…