Hydrazine hydrate (1:1) → O-Benzylhydroxylamine

HRID 1959627Notes

Reaction equation

HRID 1959627 reaction equation
[CH2:1]([O:8][N:9]1C(=O)C2C(=CC=CC=2)C1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.NN>>[CH2:1]([O:8][NH2:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 255292N-Benzyloxyphthalimide

Product 1

HCID 102313O-BenzylhydroxylamineYield 64%

Procedure

The title compound was prepared from 2-(benzyloxy)isoindoline-1,3-dione and hydrazine monohydrate in 64% yield using the same procedure as described in the synthesis of intermediate G. 1H-NMR (400 MHz, CDCl3) δ ppm 7.37 (m, 5H), 6.70 (s, 2H).

Sources & evidence

ORD record
ord-f1a1c170837c4e9391e84901aa090197
Source dataset
uspto-grants-2013_04
Patent number
US08410264B2

Reaction notes

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