Benzene → 1-(1-Naphthoyl)-3-(RS)-(4-(4-fluorophenyl)-piperidinyl-1-ethyl)-4-(RS)-(3-thienyl)pyrrolidine
Reaction equation
[Br-:39].[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:40][Mg+:41].[ClH:38].[F:25][c:26]1[cH:27][cH:28][c:29]([CH:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[cH:30][cH:31]1.[OH2:53].[c:1]1([C:11](=[O:12])[N:13]2[CH2:14][CH:15]([CH:23]=[O:24])[CH:16]([c:18]3[cH:19][s:20][cH:21][cH:22]3)[CH2:17]2)[cH:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12.[cH:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[c:1]1([C:11](=[O:12])[N:13]2[CH2:14][CH:15]([CH2:23][CH2:40][N:35]3[CH2:34][CH2:33][CH:32]([c:29]4[cH:28][cH:27][c:26]([F:25])[cH:31][cH:30]4)[CH2:37][CH2:36]3)[CH:16]([c:18]3[cH:19][s:20][cH:21][cH:22]3)[CH2:17]2)[cH:2][cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-76d561dcdf8b4bafa4859cc275f105ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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