反应详情

温度

80 °C

4-Fluoro-3-(trifluoromethyl)benzonitrile (400 mg, 2.12 mmol) was suspended together with sodium methanesulfinate (216 mg, 2.12 mmol) in DMSO (2 ml) and stirred at 80° C. for 22 hours. The reaction was then cooled, diluted with 25 ml H2O and filtered. Filtered solids were evaporated from toluene to give 536 mg of the title substance (quant).

1. temperatureThe reaction was then cooled
2. filtrationfiltered
3. filtrationFiltered solids
4. customwere evaporated from toluene
5. customto give 536 mg of the title substance (quant)