Sodium periodate → HCID 66732355, compound

HRID 1963120Notes

Reaction equation

HRID 1963120 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][N:6]([C:9]([O:11][CH3:12])=[O:10])[CH:5]([CH2:13][C:14]([CH3:17])([CH3:16])[CH3:15])[CH2:4]1.I([O-])(=O)(=O)=[O:19].[Na+]>[Ru](Cl)(Cl)Cl>[CH3:12][O:11][C:9]([N:6]1[CH2:7][CH2:8][CH:3]([C:2]([OH:19])=[O:1])[CH2:4][CH:5]1[CH2:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:10]

Participants

4

Reactant 2

HCID 23667635Sodium periodateHCID 667316611-Piperidinecarboxylic acid, 2-(2,2-dimethylpropyl)-4-(hydroxymethyl)-, methyl ester

Product 1

HCID 66732355HCID 66732355, compound

Reagents, catalysts & solvents 1

HCID 61850Ruthenium trichlorideCatalyst

Procedure

The compound was prepared as described in Reference Compound 4, Step 5 starting from methyl 4-(hydroxymethyl)-2-neopentylpiperidine-1-carboxylate, sodium periodate (15.0 g, 70.3 mmol) and ruthenium(III) chloride (0.11 g, 0.52 mmol), which resulted in the title compound. MS m/z 256 (M−H)−.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-b1b778c6b2f6451091e4e9eb38f4beb4
Source dataset
uspto-grants-2013_04
Patent number
US08415378B2

Reaction notes

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