Tetrahydrofuran → N-(4-(3-(4-Amino-6-methyl-1,3,5-triazin-2-YL)-5-chloropyridin-2-ylamino)-2-fluorophenyl)acetamide
Reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:13][Si:14]([N-:15][Si:16]([CH3:17])([CH3:18])[CH3:19])([CH3:20])[CH3:21].[Cl:23][c:24]1[cH:25][c:26](-[c:31]2[n:32][c:33]([NH2:38])[n:34][c:35]([CH3:37])[n:36]2)[c:27]([F:30])[n:28][cH:29]1.[Li+:22].[NH2:1][c:2]1[cH:3][c:4]([F:12])[c:5]([NH:8][C:9]([CH3:10])=[O:11])[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4]([F:12])[c:5]([NH:8][C:9]([CH3:10])=[O:11])[cH:6][cH:7]1)[c:27]1[c:26](-[c:31]2[n:32][c:33]([NH2:38])[n:34][c:35]([CH3:37])[n:36]2)[cH:25][c:24]([Cl:23])[cH:29][n:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-45f9d18a334b4a1ba230ff9eaed1ea69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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