Hydrochloric Acid → HCID 6419992, compound

HRID 1966053Notes

Reaction equation

HRID 1966053 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][C:12]([F:15])([F:14])[F:13])[CH:8]=[CH:7][C:5]=2[N:6]=1.[ClH:16]>CO>[ClH:16].[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][C:12]([F:15])([F:13])[F:14])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 5070Riluzole

Product 1

HCID 6419992HCID 6419992, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 2-amino-6-(trifluoromethoxy)-benzothiazole in methanol (10 ml) is added 37% HCl (1 ml) dropwise, and the precipitate recrystallised from methanol to give quantitative yield of the hydrochloride, as white needles, m.p.: 214-216° C.

Workup

  1. customthe precipitate recrystallised from methanol

Sources & evidence

ORD record
ord-1d33b85f8432421fbc1bc863b9216d78
Source dataset
uspto-grants-2013_04
Patent number
US08420634B2

Reaction notes

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