Acetic Anhydride → HCID 66995475, compound

HRID 1969151Notes

Reaction equation

HRID 1969151 reaction equation
[H-].[Na+].[C:3]([O:6][C:7](=[O:9])[CH3:8])(=O)[CH3:4].OC1C=[CH:15][C:14]([C:17]2[S:21][C:20]([C:22]([O:24][CH3:25])=[O:23])=[CH:19][CH:18]=2)=[CH:13][CH:12]=1>C1COCC1>[C:7]([O:6][C:3]1[CH:12]=[CH:13][C:14]([C:17]2[S:21][C:20]([C:22]([O:24][CH3:25])=[O:23])=[CH:19][CH:18]=2)=[CH:15][CH:4]=1)(=[O:9])[CH3:8]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 24758Sodium hydrideHCID 57443285HCID 57443285, compound

Product 1

HCID 66995475HCID 66995475, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Sodium hydride and acetic anhydride were added to a THF solution of methyl 5-(4-hydroxyphenyl)thiophene-2-carboxylate and the whole was stirred at room temperature to obtain methyl 5-[4-(acetyloxy)phenyl]thiophene-2-carboxylate. ES: 277.

Sources & evidence

ORD record
ord-11141c93ee44444c87097b8e673d4b60
Source dataset
uspto-grants-2013_04
Patent number
US08426453B2

Reaction notes

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