Ammonium → 1-Benzyl-4-[4-(tetrahydropyran-2-yloxy)phenyl]piperidin-4-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH:7]2[O:8][CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:13][cH:14]1.[CH2:15]([Li:16])[CH2:17][CH2:18][CH3:19].[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[N:27]1[CH2:28][CH2:29][C:30](=[O:33])[CH2:31][CH2:32]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[Cl-:34].[NH4+:35]>>[c:2]1([C:30]2([OH:33])[CH2:29][CH2:28][N:27]([CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:32][CH2:31]2)[cH:3][cH:4][c:5]([O:6][CH:7]2[O:8][CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:13][cH:14]1Participants
7
Sources & evidence
- ORD record
- ord-6925b214bd844411bfe475157636af47
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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