METHYLPHENYLPHOSPHINIC ACID → HCID 66627126, compound

HRID 1970713Notes

Reaction equation

HRID 1970713 reaction equation
[CH3:1][P:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:4])[OH:3].[OH-].[CH2:12]([N+:16]([CH2:25][CH2:26][CH2:27][CH3:28])([CH2:21][CH2:22][CH2:23][CH3:24])[CH2:17][CH2:18][CH2:19][CH3:20])[CH2:13][CH2:14][CH3:15]>O.CC(O)C>[CH3:1][P:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:3])[O-:4].[CH2:25]([N+:16]([CH2:12][CH2:13][CH2:14][CH3:15])([CH2:17][CH2:18][CH2:19][CH3:20])[CH2:21][CH2:22][CH2:23][CH3:24])[CH2:26][CH2:27][CH3:28]

Participants

5

Reactant 2

HCID 345468METHYLPHENYLPHOSPHINIC ACIDHCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 66627126HCID 66627126, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3776IsopropanolSolvent

Procedure

To a flask were added 2.0 g methylphenylphosphinic acid, 5.4 g of a 55-60% solution of tetrabutylammonium hydroxide in water and 25 ml 2-propanol. After heating to 50 C under nitrogen for 1 hour, the solvent was removed and another 20 ml of 2-propanol were added and removed by distillation under reduced pressure. After drying, an oil was obtained.

Workup

  1. temperatureAfter heating to 50 C under nitrogen for 1 hour
  2. customthe solvent was removed
  3. additionanother 20 ml of 2-propanol were added
  4. customremoved by distillation under reduced pressure
  5. customAfter drying
  6. customan oil was obtained

Sources & evidence

ORD record
ord-ca02437653ab4d33880bae8d79a92ffa
Source dataset
uspto-grants-2013_04
Patent number
US08431045B2

Reaction notes

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