反应详情

To a solution of the product of example 5 (200 mg, 0.357 mmol) in acetonitrile (3 ml), carbon tetrachloride (330 mg, 2.1 mmol), triethylamine (180 mg, 1.78 mmol) and triphenylphosphine (470 mg, 1.79 mmol) were added successively at room temperature. The mixture was stirred for 3 hours. The product was purified by column chromatography (CH2Cl2/MeOH=150/1) to give the titled product (40 mg, 21% yield).

1. customThe product was purified by column chromatography (CH2Cl2/MeOH=150/1)