Methyl Benzoate → HCID 67530536, compound

HRID 1972111Notes

Reaction equation

HRID 1972111 reaction equation
[C:1](OC)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]([OH:18])[CH3:17]>C1(C)C=CC=CC=1>[C:1]([O:18][CH:16]([CH2:15][CH2:14][CH2:13][CH2:12][NH2:11])[CH3:17])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7150Methyl BenzoateHCID 18957288HCID 18957288, compound

Product 1

HCID 67530536HCID 67530536, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In an argon atmosphere, a mixture of methyl benzoate (1.0 mmol), 6-aminohexan-2-ol (1.2 mmol), Zn4(OCOCF3)6O (1.25 mol % in terms of mole number) and toluene (1.7 ml) was heated to reflux for 46 hours, and as a result, 6-amino-2-hexyl benzoate was obtained at a yield of 66%. The yield of 6-benzoylamino-2-hexyl benzoate was 21%.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 46 hours

Sources & evidence

ORD record
ord-d0ab2f60eed849aca2051af5d2b78116
Source dataset
uspto-grants-2013_04
Patent number
US08431709B2

Reaction notes

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