Dichloromethane → [3-Methyl-4-(1-phenylpyrido[3,4-d]pyridazin-4-yl)piperazin-1-yl]-morpholin-4-ylmethanone

HRID 197303Notes

Reaction equation

HRID 197303 reaction equation
[CH3:1][CH:2]1[N:3]([c:8]2[n:9][n:10][c:11](-[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:12]3[c:13]2[cH:14][n:15][cH:16][cH:17]3)[CH2:4][CH2:5][NH:6][CH2:7]1.[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[Cl:40][CH2:41][Cl:42].[O:31]1[CH2:32][CH2:33][N:34]([C:37](=[O:38])[Cl:39])[CH2:35][CH2:36]1>>[CH3:1][CH:2]1[N:3]([c:8]2[n:9][n:10][c:11](-[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:12]3[c:13]2[cH:14][n:15][cH:16][cH:17]3)[CH2:4][CH2:5][N:6]([C:37]([N:34]2[CH2:33][CH2:32][O:31][CH2:36][CH2:35]2)=[O:38])[CH2:7]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 848104-Morpholinecarbonyl chlorideHCID 687473394-(2-Methylpiperazin-1-yl)-1-phenylpyrido[3,4-d]pyridazine

Product 1

HCID 68745605[3-Methyl-4-(1-phenylpyrido[3,4-d]pyridazin-4-yl)piperazin-1-yl]-morpholin-4-ylmethanone

Sources & evidence

ORD record
ord-d165e990800a49808292ff75549f8b52
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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