Potassium Carbonate → HCID 20336751, compound

HRID 1973513Notes

Reaction equation

HRID 1973513 reaction equation
[C:1]1([S:7]([O-:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Na+].C(=O)([O-])[O-].[K+].[K+].Br[CH2:18][CH:19]=[C:20]1[CH2:24][CH2:23][CH2:22][CH2:21]1>[I-].[Na+].CO>[C:20]1(=[CH:19][CH2:18][S:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)(=[O:9])=[O:8])[CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

6

Reactant 3

HCID 11430Potassium CarbonateHCID 2723840Benzenesulfinic acid, sodium saltHCID 12772662(2-Bromoethylidene)cyclopentane

Product 1

HCID 20336751HCID 20336751, compoundYield 47.1%

Reagents, catalysts & solvents 2

HCID 5238Sodium IodideCatalystHCID 887MethanolSolvent

Conditions

Temperature
20 °C

Procedure

22.3 gm of sodium phenyl sulfinate, 2.2 gm of potassium carbonate and 0.2 gm of sodium iodide were introduced into 50 cc of methanol. Then 23.6 gm of 1-bromo-2-cyclopentylidene-ethane were added at a temperature of about +10° C and under agitation and the reaction mixture was agitated for 2 hours at 20° C. Thereafter, the reaction mixture was poured into ice water and cooled to 0° C. The precipitate formed was isolated by vacuum filtering and dried under vacuum in the presence of potassium hydroxide to obtain 15 gm of (2-cyclopentylidene-ethyl)-phenyl sulfone having a melting point of 68° C. A sample of the product crystallized from isopropyl ether had a melting point of 68° C.

Workup

  1. temperaturecooled to 0° C
  2. customThe precipitate formed
  3. customwas isolated by vacuum
  4. filtrationfiltering
  5. dry with materialdried under vacuum in the presence of potassium hydroxide

Sources & evidence

ORD record
ord-dd9c6c8f068e45e89f3af3ce476db394
Source dataset
uspto-grants-1976_12
Patent number
US03997586

Reaction notes

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