反应详情

To 26 parts 4-hydroxymethyl-2,5-diisopropylbenzenesulfonamide dissolved in 100 parts chloroform heated just below reflux is added hydrogen bromide in a slow stream for an hour. The organic phase is washed with aqueous sodium bicarbonate, dried over magnesium sulfate and concentrated in vacuo to give 4-bromomethyl-2,5-diisopropylbenzenesulfonamide.

1. temperatureheated just
2. temperaturebelow reflux
3. washThe organic phase is washed with aqueous sodium bicarbonate
4. dry with materialdried over magnesium sulfate
5. concentrationconcentrated in vacuo