Tetrahydrofuran → tert-butyl 5-hydroxy-3-oxo-2-(1-phenylethyl)-3a,4,5,6-tetrahydro-1H-cyclopenta[c]pyrrole-6a-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]1([CH2:22][CH:23]2[O:24][CH2:25]2)[CH2:9][N:10]([CH:14]([CH3:15])[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[C:11](=[O:13])[CH2:12]1.[CH3:26][Si:27]([CH3:28])([CH3:29])[N-:30][Si:31]([CH3:32])([CH3:33])[CH3:34].[Li+:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]12[CH2:9][N:10]([CH:14]([CH3:15])[c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[C:11](=[O:13])[CH:12]1[CH2:25][CH:23]([OH:24])[CH2:22]2Participants
5
Sources & evidence
- ORD record
- ord-c02b29640b8e4d7cae6088c9a3f3ea9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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