Allylamine → HCID 21490733, compound

HRID 1973889Notes

Reaction equation

HRID 1973889 reaction equation
[C:1]([OH:13])(=O)[CH2:2][CH:3]1[CH:11]=[CH:10][CH2:9][CH2:8][CH:4]1[C:5]([OH:7])=O.[CH2:14]([NH2:17])[CH:15]=[CH2:16]>>[CH2:14]([N:17]1[C:1](=[O:13])[CH2:2][C:3]2[CH2:11][CH2:10][CH2:9][CH2:8][C:4]=2[C:5]1=[O:7])[CH:15]=[CH2:16]

Participants

3

Reactant 2

HCID 7853AllylamineHCID 131710580HCID 131710580, compound

Product 1

HCID 21490733HCID 21490733, compound

Procedure

A mixture of tetrahydrohomophthalic acid (9.2 g., 0.05 mole) and allylamine (2.8 g., 0.05 mole) is heated by an oil bath until molten for 40 minutes. The mixture solidifies upon cooling, and is recrystallized twice from isopropanol, giving 2-allyl-5,6,7,8-tetrahydroisoquinoline-1,3(2H, 4H)-dione.

Workup

  1. temperatureis heated by an oil bath until molten for 40 minutes
  2. temperatureupon cooling
  3. customis recrystallized twice from isopropanol

Sources & evidence

ORD record
ord-dc18d779806e4351ac8fc00a11e9100e
Source dataset
uspto-grants-1976_12
Patent number
US03998954

Reaction notes

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