Hydrochloric Acid → 2-Phenyl-1H-indole-3-carbaldehyde

HRID 1974044Notes

Reaction equation

HRID 1974044 reaction equation
[C:1]1([C:7]2[NH:8][C:9]3[C:14]([C:15]=2[CH:16]2N(C4C=CC=CC=4)CCN2C2C=CC=CC=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([OH:36])(C)C.Cl>O>[CH:16]([C:15]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[O:36]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 21488639HCID 21488639, compound

Product 1

HCID 6133052-Phenyl-1H-indole-3-carbaldehyde

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.0 parts by weight of 2-(2-phenylindol-3-yl)-1,3-diphenyl imidazolidine are suspended in 10 parts by volume of isopropanol and 4 parts by volume of 10% aqueous hydrochloric acid added. Thereafter water is added and 1.7 parts by weight of 3-formyl-2-phenyl indole are obtained by filtering off.

Workup

  1. additionadded

Sources & evidence

ORD record
ord-ee96244d81fc4df9838d4878f18d9601
Source dataset
uspto-grants-1976_12
Patent number
US04000152

Reaction notes

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