反应详情

Three and eight-tenths grams (3.8 g.) (0.025 m.) of p-hydroxyphenylisothiocyanate was mixed with 2.5 g. (0.025 m.) of n-butylisocyanate in 50 mls. of benzene. To this mixture was added 3 drops each of triethylamine and dibutyltin dilaurate, and the mixture was allowed to stand at ambient temperature over night. After refluxing on the steam-bath for thirty minutes, the solvent was removed under vacuum by means of a rotary evaporator. The residue was slurried in n-hexane, filtered and air dried. There was obtained 5.4 grams of solid, m.p. 99°-102° C. The structure was confirmed by I.R.

1. waitto stand at ambient temperature over night
2. temperatureAfter refluxing on the steam-bath for thirty minutes
3. customthe solvent was removed under vacuum by means of a rotary evaporator
4. filtrationfiltered
5. customair dried