Bicarbonate Ion → 2-fluoro-N-[[1-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]indol-6-yl]methyl]acetamide

HRID 197470Notes

Reaction equation

HRID 197470 reaction equation
[C:1]([Cl:2])(=[O:3])[O:4][CH2:5][CH3:6].[C:39](=[O:40])([OH:41])[O-:42].[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[CH3:49][CH2:50][O:51][C:52](=[O:53])[CH3:54].[F:13][c:14]1[cH:15][cH:16][c:17]([CH2:18][CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([n:26]3[cH:27][cH:28][c:29]4[cH:30][cH:31][c:32]([CH2:35][NH2:36])[cH:33][c:34]34)[CH2:24][CH2:25]2)[cH:37][cH:38]1.[Na+:43].[Na+:7].[O-:8][C:9](=[O:10])[CH2:11][F:12]>>[O:8]=[C:9]([CH2:11][F:12])[NH:36][CH2:35][c:32]1[cH:31][cH:30][c:29]2[cH:28][cH:27][n:26]([CH:23]3[CH2:22][CH2:21][N:20]([CH2:19][CH2:18][c:17]4[cH:16][cH:15][c:14]([F:13])[cH:38][cH:37]4)[CH2:25][CH2:24]3)[c:34]2[cH:33]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 5236Fluoroacetate anionHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 10928Ethyl chloroformateHCID 22038390HCID 22038390, compound

Product 1

HCID 220382092-fluoro-N-[[1-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]indol-6-yl]methyl]acetamide

Sources & evidence

ORD record
ord-5c8636dca01346f3ab616110a90672f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…