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HRID1974908

反应详情

EQUATION

反应方程式

HRID 1974908 的结构方程式

REACTANTS

反应物

2
结构：CC(C)C[C@H](OC(=O)Cl)C(=O)OCc1ccccc1
HCID57259964

未命名化合物

结构：CN(C)C(=O)[C@@H](N)C(C)(C)C.Cl
HCID86751143

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)C[C@H](OC(=O)N[C@H](C(=O)N(C)C)C(C)(C)C)C(=O)OCc1ccccc1
HCID67641539

未命名化合物

收率 85.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

(2S)-2-Amino-3,3-dimethyl-N,N-dimethylbutyramide hydrochloride (0.25 g), (2S)-2-chlorocarbonyloxy-4-methylvaleric acid benzyl ester (0.36 g) and TEA (0.31 g) were reacted in ethyl acetate (10 ml) in a similar manner to that of Example 4-1) to give (2S)-2-[N-[(1S)-2,2-dimethyl-1-(N,N-dimethylcarbamoyl)propyl]carbamoyloxy]-4-methylvaleric acid benzyl ester (0.44 g).