Iodoethane → HCID 22406593, compound

HRID 1975688Notes

Reaction equation

HRID 1975688 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.[CH2:12](I)[CH3:13].[CH2:15](Br)[CH:16]=[CH2:17]>>[CH2:17]([C:9]([C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)([CH2:12][CH3:13])[C:10]#[N:11])[CH:16]=[CH2:15]

Participants

4

Reactant 3

HCID 6340IodoethaneHCID 7841Allyl bromideHCID 88310(3-Methoxyphenyl)acetonitrile

Product 1

HCID 22406593HCID 22406593, compoundYield 46%

Procedure

The procedures described in the portion of Example 1 which is concerned with the preparation of starting materials were repeated except that 3-methoxyphenylacetonitrile was alkylated in turn with ethyl iodide and allyl bromide. The 2-allyl-2-(3-methoxyphenyl)butyronitrile so obtained was treated with boron tribromide to give the required starting material in an overall yield of 46% as a gum.

Workup

  1. customis concerned with the preparation of starting materials

Sources & evidence

ORD record
ord-5879d0a2b3aa49309709f06bc84ba5ef
Source dataset
uspto-grants-1994_02
Patent number
US05288742

Reaction notes

Loading…