2-Chlorobenzaldehyde → 1-(2-Chlorophenyl)-2-heptanone

HRID 1975702Notes

Reaction equation

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[N+](CCCCCC)([O-])=O.F[C:20]1[CH:27]=[CH:26][CH:25]=C[C:21]=1[CH:22]=[O:23].[N+](CCC)([O-])=O>>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][C:22](=[O:23])[CH2:21][CH2:20][CH2:27][CH2:26][CH3:25]

Participants

Reactant 4

HCID 69962-Chlorobenzaldehyde

HCID 79031-Nitropropane

HCID 125891-Nitrohexane

HCID 67970o-Fluorobenzaldehyde

Product 1

HCID 152899391-(2-Chlorophenyl)-2-heptanoneYield 17%

Procedure

Following a procedure similar to that described in Preparation 9, except that equivalent amounts of 2-chlorobenzaldehyde and nitrohexane were used in place of the 2-fluorobenzaldehyde and nitropropane, the title compound was obtained as a pale yellow oil in a yield of 17%.

Sources & evidence

ORD record: ord-809ec52a031041cb93383a84c4655ebb
Source dataset: uspto-grants-1994_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05288726

Reaction notes

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