Sodium → HCID 54132819, compound

HRID 1975833Notes

Reaction equation

HRID 1975833 reaction equation
[SH:1][C:2]1[NH:3][C:4]2[CH:9]=[CH:8][N:7]=[CH:6][C:5]=2[N:10]=1.[Na].[C:12]([O:20][C:21]1[CH:26]=[C:25]([CH2:27]Br)[CH:24]=[C:23]([O:29][C:30](=[O:37])[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:22]=1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:30]([O:29][C:23]1[CH:24]=[C:25]([CH2:27][S:1][C:2]2[NH:10][C:5]3[CH:6]=[N:7][CH:8]=[CH:9][C:4]=3[N:3]=2)[CH:26]=[C:21]([O:20][C:12](=[O:19])[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:22]=1)(=[O:37])[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1

Participants

4

Reactant 3

HCID 5360545SodiumHCID 19098804HCID 19098804, compoundHCID 178527813HCID 178527813, compound

Product 1

HCID 54132819HCID 54132819, compound

Procedure

The synthesis of this compound proceeded in the same fashion as Example 15 using 1.66 g (0.011 mol) of 2-mercapto-1H-imidazo[4,5-c]pyridine, 0.28 g (0.012 g atom) of sodium and 4.51 g (0.011 mol) of 5-bromomethyl-benzene-1,3-diol dibenzoate. The crude material (4.2 g) when subjected to HPLC gave pure product (m.p. 209°-212° C.).

Workup

  1. customThe synthesis of this compound

Sources & evidence

ORD record
ord-a7edbfb5ecdb4efab4abda29a54bb643
Source dataset
uspto-grants-1994_02
Patent number
US05288871

Reaction notes

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