Ethyl Acetate → tert-butyl 4-(7-acetoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate

HRID 197670Notes

Reaction equation

HRID 197670 reaction equation
[C:15](=[O:16])([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[N:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH2:6][CH2:7][c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[Cl:14].[CH3:28][N:29]1[CH2:30][CH2:31][CH2:32][C:33]1=[O:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40]>>[C:1]([CH3:2])(=[O:3])[O:4][CH:5]1[CH2:6][CH2:7][c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[N:25]1[CH2:24][CH2:23][N:22]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:27][CH2:26]1

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 13387N-methyl-2-pyrrolidoneHCID 143452tert-Butyl piperazine-1-carboxylateHCID 199689354-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-7-yl acetate

Product 1

HCID 59671081tert-butyl 4-(7-acetoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-95ece18ea39a43f1b8a0a8e67d8cac5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…