Hydrochloric Acid → 5-chloro-N-cyclopentyl-2-[4-(2-piperazin-1-ylethyl)-4,5-dihydro-1,3-thiazol-2-yl]-1H-indol-7-amine

HRID 197735Notes

Reaction equation

HRID 197735 reaction equation
[C:37]([O:38][CH2:39][CH3:40])(=[O:41])[CH3:42].[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][N:27]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:28][CH2:29]4)[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1.[Cl:44][CH2:45][Cl:46].[ClH:43]>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][c:6]([C:17]3=[N:21][CH:20]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]4)[CH2:19][S:18]3)[nH:7][c:8]2[c:9]([NH:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[cH:10]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 178452325HCID 178452325, compound

Product 1

HCID 669743005-chloro-N-cyclopentyl-2-[4-(2-piperazin-1-ylethyl)-4,5-dihydro-1,3-thiazol-2-yl]-1H-indol-7-amine

Sources & evidence

ORD record
ord-fca7cc9acb324ff39f51d8e79953b27e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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