Ethyl Acetate → HCID 135815253, compound

HRID 1977629Notes

Reaction equation

[CH2:1]([NH:3][C:4]1[CH:24]=[CH:23][C:7]([CH2:8][C:9]2[NH:10][C:11](=[O:22])[C:12]3[N:17]([CH3:18])[N:16]=[C:15]([CH2:19][CH2:20][CH3:21])[C:13]=3[N:14]=2)=[CH:6][CH:5]=1)[CH3:2].[C:25](OCC)(=[O:27])[CH3:26]>>[CH2:1]([N:3]([C:4]1[CH:24]=[CH:23][C:7]([CH2:8][C:9]2[NH:10][C:11](=[O:22])[C:12]3[N:17]([CH3:18])[N:16]=[C:15]([CH2:19][CH2:20][CH3:21])[C:13]=3[N:14]=2)=[CH:6][CH:5]=1)[C:25](=[O:27])[CH3:26])[CH3:2]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 135815258HCID 135815258, compound

Product 1

HCID 135815253HCID 135815253, compound

Procedure

The title compound was prepared from 5-[4-(ethylamino)benzyl]-1-methyl-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one following the procedure described in Example 47 and was obtained, after trituration with ethyl acetate as a solid (59%), m.p.149-151° C.

Workup

customwas obtained

Sources & evidence

ORD record: ord-812329323bc5438bae63339d577e3c4b
Source dataset: uspto-grants-2001_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06235742B1

Reaction notes

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