反应详情

A solution of 2-[3-(7-methoxy-3,4-dihydronaphthalen-1-yl)propyl]isoindole-1,3-dione (11.8 g, 34.0 mmol) and hydrazine monohydrate (5.1 g, 0.1 mol) in ethanol (150 ml) was refluxed for 1 hour and then cooled in an ice bath. The resulting insoluble material was removed by filtration and the solvent was removed in vacuo to afford the titled compound (5.7 g, yield 77%, oil). This compound was provided for the next reaction without further purification.

1. temperaturecooled in an ice bath
2. customThe resulting insoluble material was removed by filtration
3. customthe solvent was removed in vacuo