HCID 86195276, compound → HCID 21997027, compound

HRID 1978218Notes

Reaction equation

HRID 1978218 reaction equation
[CH2:1]([S:5]([CH2:8][CH:9]([CH2:15][S:16]([CH2:19][CH2:20][CH2:21][CH3:22])(=[O:18])=[O:17])[C:10]([O:12]CC)=[O:11])(=[O:7])=[O:6])[CH2:2][CH2:3][CH3:4]>Cl>[CH2:1]([S:5]([CH2:8][CH:9]([CH2:15][S:16]([CH2:19][CH2:20][CH2:21][CH3:22])(=[O:18])=[O:17])[C:10]([OH:12])=[O:11])(=[O:6])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 86195276HCID 86195276, compound

Product 1

HCID 21997027HCID 21997027, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A mixture of 2-[(n-butylsulfonyl)methyl)-3-(n-butylsulfonyl)-propanoic acid, ethyl ester (1.0 g, 3.0 mmol) in 6N hydrochloric acid ( 20 mL) is refluxed overnight. The mixture is transferred to distilled water and extracted with ethyl acetate. The combined organic extracts are concentrated in vacuo to yield the title compound as a clear, colorless oil.

Workup

  1. temperatureis refluxed overnight
  2. distillationto distilled water
  3. extractionextracted with ethyl acetate
  4. concentrationThe combined organic extracts are concentrated in vacuo

Sources & evidence

ORD record
ord-8fb333f335fd4a3aa249652a3f1b0642
Source dataset
uspto-grants-2001_05
Patent number
US06235928B1

Reaction notes

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