Hydrogen Bromide → HCID 21996660, compound

HRID 1978299Notes

Reaction equation

HRID 1978299 reaction equation
Br.C1(C)C=C(C)C=C(C)C=1S([N:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N:21](S(C1C(C)=CC(C)=CC=1C)(=O)=O)[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][N:27](S(C1C(C)=CC(C)=CC=1C)(=O)=O)[CH2:28][CH3:29])[CH2:14][CH3:15])(=O)=O.C1(O)C=CC=CC=1.C(Cl)(Cl)[Cl:63]>>[ClH:63].[ClH:63].[ClH:63].[CH3:29][CH2:28][NH:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][NH:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][NH:13][CH2:14][CH3:15]

Participants

5

Reactant 4

HCID 260Hydrogen BromideHCID 996PhenolHCID 6212ChloroformHCID 10747861HCID 10747861, compound

Product 1

HCID 21996660HCID 21996660, compoundYield 77%

Procedure

HBr (30% in HOAc, 20 mL), 56 (2.9 g, 3.67 mmol), and phenol (3.25 g, 34.5 mmol) in CHCl3 (27 mL) were reacted, and product was isolated by the method of 2 to give 1.0 g (77%) of 26 as white crystals: NMR (D2O) δ 1.28 (t, 6 H, J=7), 1.45 (m, 4 H), 1.73 (m, 8 H), 3.08 (m, 12 H). Anal. (C14H36Cl3N3) C, H, N.

Workup

  1. customproduct was isolated by the method of 2

Sources & evidence

ORD record
ord-a9f53c6534b5434d8ce4dd72a6b2eff5
Source dataset
uspto-grants-2001_05
Patent number
US06235794B1

Reaction notes

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