Hydrogen Bromide → HCID 21996672, compound

HRID 1978305Notes

Reaction equation

HRID 1978305 reaction equation
Br.C1(C)C=C(C)C=C(C)C=1S([N:13]([CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][N:21](S(C1C(C)=CC(C)=CC=1C)(=O)=O)[CH2:22][CH2:23][CH2:24][CH2:25][N:26](S(C1C(C)=CC(C)=CC=1C)(=O)=O)[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][N:32](S(C1C(C)=CC(C)=CC=1C)(=O)=O)[CH2:33][CH3:34])[CH2:14][CH3:15])(=O)=O.C1(O)C=CC=CC=1.C(Cl)[Cl:80]>>[ClH:80].[ClH:80].[ClH:80].[ClH:80].[CH3:34][CH2:33][NH:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][NH:26][CH2:25][CH2:24][CH2:23][CH2:22][NH:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][NH:13][CH2:14][CH3:15]

Participants

5

Reactant 4

HCID 260Hydrogen BromideHCID 996PhenolHCID 6344DichloromethaneHCID 10581933HCID 10581933, compound

Product 1

HCID 21996672HCID 21996672, compoundYield 81%

Procedure

HBr (30% in HOAc, 195 mL), 79 (12.66 g, 12.1 mmol), and phenol (33.61 g, 0.357 mol) in CH2Cl2 (135 mL) were reacted, and product was isolated by the method of 2 to provide 4.50 g (81%) of 29 as white crystals: NMR (D2O) δ 1.28 (t, 6 H, J=7), 1.40-1.52 (m, 4 H), 1.66-1.80 (m, 12 H), 3.00-3.14 (m, 16 H). Anal. (C18H46Cl4N4).

Workup

  1. customproduct was isolated by the method of 2

Sources & evidence

ORD record
ord-4bbb188d4a6340a6bfeb330dd360a0f8
Source dataset
uspto-grants-2001_05
Patent number
US06235794B1

Reaction notes

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