Hydrochloric Acid → HCID 21994001, compound

HRID 1978315Notes

Reaction equation

HRID 1978315 reaction equation
C(OC([NH:8][CH2:9][CH:10]1[CH2:15][CH2:14][CH2:13][N:12]([CH2:16][CH2:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:11]1)=O)(C)(C)C.[ClH:25]>CO>[ClH:25].[ClH:25].[C:19]1([CH2:18][CH2:17][CH2:16][N:12]2[CH2:13][CH2:14][CH2:15][CH:10]([CH2:9][NH2:8])[CH2:11]2)[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21994196HCID 21994196, compound

Product 1

HCID 21994001HCID 21994001, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 50 ml of methanol was dissolved 8.902 g of N-tert-butoxycarbonyl-[1-(3-phenylpropan-1-yl)piperidin-3-ylmethyl]amine, followed by addition of 10 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 3 hours. This reaction mixture was concentrated to provide the title compound.

Workup

  1. concentrationThis reaction mixture was concentrated

Sources & evidence

ORD record
ord-846c857edee842d59a5b49c05b6946cb
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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