Hydrochloric Acid → HCID 21993757, compound

HRID 1978434Notes

Reaction equation

HRID 1978434 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][NH:16][C:17]([C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)=[O:18])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:31]>C(O)C>[ClH:31].[ClH:31].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][NH:16][C:17]([C:19]2[S:29][C:28]3[N:30]4[C:21](=[CH:22][N:23]=[C:24]4[CH:25]=[CH:26][CH:27]=3)[CH:20]=2)=[O:18])[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21993976HCID 21993976, compound

Product 1

HCID 21993757HCID 21993757, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 3.37 g (7.86 mM) of N-[2-(1-tert-butoxycarbonyl-4-piperidyl)ethyl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (100 ml) was added 12N-hydrochloric acid (3.2 ml, 39.3 mM) and the mixture was stirred at room temperature for 1 hour. The resulting crystals were collected by filtration and rinsed with small amounts of ethanol and ether to provide the title compound.

Workup

  1. filtrationThe resulting crystals were collected by filtration
  2. washrinsed with small amounts of ethanol and ether

Sources & evidence

ORD record
ord-aa6cad4bb6cb4d30963301475666ddea
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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