Hydrochloric Acid → HCID 21993852, compound

HRID 1978505Notes

Reaction equation

HRID 1978505 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:16][S:17]/[CH:18]=[CH:19]/[C:20]3[S:30][C:29]4[N:31]5[C:22](=[CH:23][N:24]=[C:25]5[CH:26]=[CH:27][CH:28]=4)[CH:21]=3)[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:32]>CO>[ClH:32].[ClH:32].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][S:17]/[CH:18]=[CH:19]/[C:20]3[S:30][C:29]4[N:31]5[C:22](=[CH:23][N:24]=[C:25]5[CH:26]=[CH:27][CH:28]=4)[CH:21]=3)[CH2:14][CH2:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21993692HCID 21993692, compound

Product 1

HCID 21993852HCID 21993852, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 2 ml of methanol was dissolved 0.233 g of (E)-4-[2-[1-(3-phenylpropan-1-yl)piperidin-4-ylmethylthio]-vinyl]-5-thia-1,8b-diazaacenaphthylene, followed by addition of a stoichiometric excess of methanolic hydrochloric acid, and the mixture was stirred for 10 minutes. This reaction mixture was concentrated to provide the title compound.

Workup

  1. concentrationThis reaction mixture was concentrated

Sources & evidence

ORD record
ord-a831a051a01640f390dfb8cfb7ccfce8
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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