Hydrochloric Acid → HCID 70247634, compound

HRID 1978508Notes

Reaction equation

HRID 1978508 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:16][NH:17][S:18](/[CH:21]=[CH:22]/[C:23]3[S:33][C:32]4[N:34]5[C:25](=[CH:26][N:27]=[C:28]5[CH:29]=[CH:30][CH:31]=4)[CH:24]=3)(=[O:20])=[O:19])[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:35]>CO>[ClH:35].[ClH:35].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][NH:17][S:18](/[CH:21]=[CH:22]/[C:23]3[S:33][C:32]4[N:34]5[C:25](=[CH:26][N:27]=[C:28]5[CH:29]=[CH:30][CH:31]=4)[CH:24]=3)(=[O:20])=[O:19])[CH2:14][CH2:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70246921HCID 70246921, compound

Product 1

HCID 70247634HCID 70247634, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 2 ml of methanol was dissolved 0.217 g of (E)-N-[1-(3-phenylpropan-1-yl)piperidin-4-ylmethyl]-2-(5-thia-1,8b-diazaacenaphthylen-4-yl)vinylsulfonamide, followed by addition of a stoichiometric excess of methanolic hydrochloric acid, and the mixture was stirred for 10 minutes. This reaction mixture was concentrated to provide the title compound.

Workup

  1. concentrationThis reaction mixture was concentrated

Sources & evidence

ORD record
ord-52d9181115534013823e5f6a9622d8f2
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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