4-Toluenesulfonyl chloride → HCID 18761631, compound

HRID 1978991Notes

Reaction equation

HRID 1978991 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH2:11][CH3:12])=[CH:5]2.[C:13]1([CH3:23])[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>C(N(CC)CC)C>[CH2:11]([C:6]1[NH:7][C:8]2[C:4]([CH:5]=1)=[CH:3][C:2]([NH:1][S:19]([C:16]1[CH:17]=[CH:18][C:13]([CH3:23])=[CH:14][CH:15]=1)(=[O:21])=[O:20])=[CH:10][CH:9]=2)[CH3:12]

Participants

4

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 22708335HCID 22708335, compound

Product 1

HCID 18761631HCID 18761631, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The above compound could be synthesized by treating 5-amino-2-ethylindole with p-toluenesulfonyl chloride in the presence of triethylamine.

Workup

  1. customThe above compound could be synthesized

Sources & evidence

ORD record
ord-60274af1aabb4aea918b3932df3c770a
Source dataset
uspto-grants-2001_05
Patent number
US06239161B1

Reaction notes

Loading…