Methyl iodide → HCID 13477852, compound

HRID 1980214Notes

Reaction equation

HRID 1980214 reaction equation
[F:1][CH:2]([F:22])[O:3][C:4]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:5]=1[CH2:6][S:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N+:11]=1[O-:16])(=[O:9])=[O:8].[H-].[Na+].[CH3:25]I>CN(C)C=O>[F:22][CH:2]([F:1])[O:3][C:4]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:5]=1[CH:6]([S:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][N+:11]=1[O-:16])(=[O:8])=[O:9])[CH3:25]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 20402341HCID 20402341, compound

Product 1

HCID 13477852HCID 13477852, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In the same manner as in Example 1, 8.86 g of 2-(2-difluoromethoxy-5-chlorobenzylsulfonyl)pyridine-N-oxide, 1.11 g of 55% sodium hydride and 3.60 g of methyl iodide were mixed with 150 ml of dimethylformamide and the mixture was reacted followed by the same after-treatment as in Example 1, whereby 7.00 g of Compound No. 15 of the present invention was obtained. The product was white crystals having a melting point of from 145°-147° C.

Workup

  1. customthe mixture was reacted
  2. custom15 of the present invention was obtained
  3. customof from 145°-147° C.

Sources & evidence

ORD record
ord-505c5d2acb304ea4b0e8681e59293bac
Source dataset
uspto-grants-1985_04
Patent number
US04508561

Reaction notes

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