Diethyl Malonate → 5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-hydroxycyclohex-2-en-1-one

HRID 1980796Notes

Reaction equation

HRID 1980796 reaction equation
[CH2:1]1[CH2:10][O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:11]=[CH:12][C:13](=[O:15])[CH3:14])=[CH:4][C:3]=2[O:2]1.C(OCC)(=O)[CH2:17][C:18](OCC)=[O:19]>>[CH2:1]1[CH2:10][O:9][C:8]2[CH:7]=[CH:6][C:5]([CH:11]3[CH2:17][C:18](=[O:19])[CH:14]=[C:13]([OH:15])[CH2:12]3)=[CH:4][C:3]=2[O:2]1

Participants

3

Reactant 2

HCID 7761Diethyl MalonateHCID 541500424-(2,3-Dihydro-1,4-benzodioxin-6-yl)but-3-en-2-one

Product 1

HCID 139829375-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-hydroxycyclohex-2-en-1-one

Procedure

5-(3,4-Ethylenedioxyphenyl)-3-hydroxycyclohex-2-en-1-one was prepared from 1-(3,4-ethylenedioxyphenyl)but-1-en-3-one and diethyl malonate following essentially the same procedure as that described in Example 1 part (ii). The product was obtained as a crystalline solid, mp 188° C.

Workup

  1. customThe product was obtained as a crystalline solid, mp 188° C.

Sources & evidence

ORD record
ord-67c961ab95ed4b1b890ef0eaa530f082
Source dataset
uspto-grants-1985_04
Patent number
US04511391

Reaction notes

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