反应详情

In 1.2 ml of isopropyl alcohol there was dissolved 2-amino-5,6-dichloro-3-formylpyrazine (0.095 g) 0.0005 M) prepared in Step B, after which n-propylamine (32 g; 0.042 ml; 0.00055 M) was added, and the reaction mixture was stirred at room temperature for 20.5 hours. When water was added to the reaction mixture, product precipitated, was filtered, and dried (23 mg). Additional product precipitated, was filtered, and dried (46 mg). The product was recrystallized from ethyl acetate/hexane. Elemental Analysis for C8H11N4OCl.

1. customprepared in Step B
2. customprecipitated
3. filtrationwas filtered
4. customdried (23 mg)
5. customAdditional product precipitated
6. filtrationwas filtered
7. customdried (46 mg)
8. customThe product was recrystallized from ethyl acetate/hexane