Mandelic Acid → Benzothiazol-2-yl-phenyl-methanol

HRID 1981459Notes

Reaction equation

HRID 1981459 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[C:9](O)(=O)[CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[OH:11]>C1(C)C(C)=CC=CC=1>[OH:11][CH:10]([C:9]1[S:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[N:1]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 1292Mandelic AcidHCID 87132-Aminothiophenol

Product 1

HCID 257798Benzothiazol-2-yl-phenyl-methanol

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of o-aminothiophenol (23.5 g) and dl-mandelic acid (25 g) was refluxed in xylene with a Dean-Stark tube for two days.

Sources & evidence

ORD record
ord-40182935d6b0473fad46efb3917a219a
Source dataset
uspto-grants-1986_06
Patent number
US04592774

Reaction notes

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