N,N-Diethylaniline → HCID 23316385, compound

HRID 1982380Notes

Reaction equation

HRID 1982380 reaction equation
[Br:1][C:2]1([CH:16]=[CH:15]N=[C:13]([CH:17]([OH:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:12]1)C(NC1C=CC=CC=1)=O.[CH3:25][CH2:26][N:27](C1C=CC=CC=1)[CH2:28]C.C([N:38]([CH2:41][CH3:42])[CH2:39][CH3:40])C>>[Br:1][C:2]1[CH:16]=[CH:15][C:28]2[N:27]=[C:26]([C:25]3[CH:40]=[CH:39][N:38]=[CH:41][CH:42]=3)[O:24][CH:17]([C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:13]=2[CH:12]=1

Participants

4

Reactant 3

HCID 7061N,N-DiethylanilineHCID 8471TriethylamineHCID 86740863HCID 86740863, compound

Product 1

HCID 23316385HCID 23316385, compoundYield 85%

Procedure

4-Bromo-2-(α-hydroxybenzyl)-isonicotinanilide (12.8 g) was treated as in Synthesis 6 except that triethylamine was replaced by diethylaniline (6.0 ml). The titled compound was obtained in an amount of 10.3 g (yield: 85%).

Sources & evidence

ORD record
ord-28bd210eaf1741448a0d73690b5cf0d9
Source dataset
uspto-grants-1986_06
Patent number
US04596801

Reaction notes

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